Susan A Greenspoon, Ph.D.


Affiliate Assistant Research Professor
(804) 786-4707 ext. 20456

Susan Greenspoon received her Bachelor of Science in biology from the University of Texas at Austin and her Ph.D. in molecular biology with a minor in genetics from Indiana University at Bloomington. She followed that with a post-doc at the University of Michigan in Ann Arbor.


Professional experience
Dr. Greenspoon is a forensic molecular biologist at the Virginia Department of Forensic Science where she has been employed in that capacity since 2001. Her primary roles are to investigate new technologies, validate new technologies, develop implementation and training programs and perform statistical analyses for criminal paternity and relationship cases, as well as a number of other functions. Prior to employment at the Department, she worked as a casework examiner and the DNA Technical Manager at the Forensic Services Division of the Detroit Police Department. There, she oversaw the technical operations for the DNA unit and performed casework analysis on a wide variety of criminal cases.


Professional accomplishments
Dr. Greenspoon has been an appointed editorial board member of the Journal of Forensic Sciences since 2000. She has also been an invited reviewer for both forensic science and basic scientific journals and has published many articles in forensic journals. She has been an invited member of the AABB Relationship Testing Standards Program Unit committee since 2006, is a member of the DNA Technical Working Group for the National Institute of Justice, and is a member of the OSAC subcommittee of DNA methodology. She has presented numerous times at major forensic conferences and has testified as an expert witness in courts of law in Virginia and Michigan. She is a Fellow of the American Academy of Forensic Sciences.



  1. Greenspoon SA, Scheiermeier-Wood L and Jenkins B.  Establishing the Limits of TrueAllele® Casework:  A Validation Study.  In press, J Forensic Sci.
  2. Perlin MW, Dormer K, Hornyak J, Schiermeier-Wood L, Greenspoon S.  TrueAllele Casework on Virginia DNA Mixture Evidence: Computer and Manual Interpretation in 72 Reported Criminal Cases.  PLoS One. 2014 Mar 25;9(3):e92837. doi: 10.1371/journal.pone.0092837.
  3. Liu P, Greenspoon SA, Yeung SH, Scherer JR and Mathies RA. Integrated sample cleanup and microchip capillary array electrophoresis for high-performance forensic STR profiling.  Methods Mol Biol. 2012;830:351-65.
  4. Peng Liu, Xiujun Li, Susan A. Greenspoon, James R. Scherer and Richard A. Mathies.  Integrated purification, PCR, sample clean-up, and capillary electrophoresis microchip for forensic human identification. Lab Chip, 2011, 11, 1041.
  5. Peng Liu, James R. Scherer, Susan A. Greenspoon, Thomas N. Chiesl, Richard A. Mathies.  Integrated sample cleanup and capillary array electrophoresis microchip for forensic short tandem repeat analysis.  Forensic Sci Int: Genetics. 2011 Nov;5(5): 484-492
  6. Reedy CR, Hagan KA, Strachan BC, Higginson JJ, Bienvenue JM, Greenspoon SA, Ferrance JP, and Landers JP.  Dual-domain Microchip-based Process for Volume Reduction Solid Phase Extraction of Nucleic Acids from Dilute, Large Volume Biological Samples.  Anal Chem. 2010 Jul 1;82(13):5669-78.
  7. Reedy CR, Bienvenue JM, Coletta L, Strachan BC, Bhatri N, Greenspoon S, Landers JP. Volume Reduction Solid Phase Extraction of DNA from Dilute, Large-Volume Biological Samples.  Forensic Sci Int Genet. 2010 Apr;4(3):206-12.
  8. Grubb JC, Horsman KM, Sykes KLV, Schlisserman RA, Covert VM, Rhee HN, Ban JD and Greenspoon SA.  Implementation and Validation of the Teleshake Unit for DNA IQTM Robotic Extraction and Development of a Large Volume DNA IQTM Method.  (2010) J Forensic Sci;55(3):706-14
  9. Horsman-Hall KM, Orihuela Y, Karczynski SL; Davis A, Greenspoon SA and Ban JD.  Development of STR Profiles from Firearms and Fired Cartridge Cases. (2009) Forensic Sci Int Genetics;3(4):242-50.
  10. Stephanie H. I. Yeung, Peng Liu, Nadia Del Bueno, Susan A. Greenspoon and Richard
    A. Mathies.  Integrated Sample Cleanup–Capillary Electrophoresis Microchip for High-Performance Short Tandem Genetic Repeat Analysis. (2009) Anal Chem.;81(1):210-7.
  11. Stephanie H.I. Yeung, Igor L. Medintz, Susan A. Greenspoon and Richard A. Mathies.  Rapid Determination of Monozygous Twinning with a Microfabricated Capillary Array Electrophoresis Genetic Analysis Device. (2008) Clinical Chem;54(6):1080-4.
  12. Stephanie H.I. Yeung, Tae Seok Seo, Cecelia A. Crouse, Susan A. Greenspoon, Thomas N. Cheisl, Jeff D. Ban and Richard A. Mathies.   Fluorescence energy-transfer labeled primers for high-performance forensic DNA profiling (2008)  Electrophoresis;29:2251–2259.
  13. Greenspoon, SA, Yeung, SHI, Johnson, K, Chu WK, Rhee, HN, McGuckian, A, Crouse, C, Chiesl TN, Barron AE, Scherer, J, Ban, JD and Mathies, R.  A Forensic Lab Tests the Berkeley Microfabricated Capillary Array Electrophoresis Device (2008) J Forensic Sci.;53(4):828-37.
  14. Greenspoon SA, Yeung SHI, Ban JD and Mathies RA.  Microchip Capillary Electrophoresis:  Progress Toward an Integrated Forensic Analysis System.  Profiles in DNA (2007);10(2):16-18.
  15. Yeung, SHI, Greenspoon, SA, Ban, JD, McGuckian A, Crouse C, et al. Microfabricated Capillary Array Electrophoresis System for High-Throughput Forensic STR Typing. J Forensic Sci. (2006);51(4):740-747.
  16. Greenspoon, SA, Sykes, KLV, Ban, JD, Pollard, A, Baisden, M, Farr, M, Graham, N, Collins, BL, Green, MM, and Christenson, CC.  Automated PCR Setup for Forensic Casework Samples Using the Normalization Wizard and PCR Setup robotic methods.  Forensic Sci. Int.. 2006;164:240-248.
  17. Silvia, ML, Pomposini, DA, Rhee, HN and Greenspoon, SA.  Somatic Mutation Study of Hair Roots in an Individual. Profiles in DNA (2006);9(1):6-7.
  18. Crouse, C, Yeung, S, Greenspoon, S, McGuckian A, Sikorsky, J, Ban, J, Mathies, R.  Improving Efficiency of a Small Forensic DNA Laboratory:  Validation of Robotic Assays and Evaluation of Microcapillary Array Device.  Croat Med J 2005;46(4):563-577.
  19. Greenspoon, SA, Ban, JD, Sykes, K, Ballard, E., Edler, S., Baisden, M., and Covington, B.  Application of the BioMek 2000 Robot and the DNA IQ System to the Extraction of Forensic Casework Samples. J. of Forensic Sci (2004);49(1):29-39.
  20. Greenspoon, SA, et al.  Validation and Implementation of the PowerPlex 16 BIO System STR Multiplex for Forensic Casework Casework. J. of Forensic Sci (2004);49(1):71-80.
  21. Greenspoon, S. and Ban, J. Robotic Extraction of Mock Sexual Assault Samples Using the BioMek® 2000 and the DNA IQ™ System. Profiles in DNA (2002);5(1):3-5.
  22. Greenspoon, SA, Lytle, PJ, Turek, SA, Rolands, J, Scarpetta, MA, and Carr, C. Validation of the PowerPlex 1.1 Loci for Use in Human Identification.  J. of Forensic Sci (2000); 45(3):  677-683.
  23. Greenspoon, SA., Scarpetta, MA, Drayton, ML.,Turek, SA.  QIAamp Spin Columns as a Method of DNA Isolation for Forensic Casework.  J. of Forensic Sci (1998); 43(5): 1024-1030.